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Carpenter’s syndrome: Development problems that include premature fusion of craniosynostosis (skull bones) and finger and toe abnormalities are characterized as carpenter’s syndrome.One gene of the first 22 non-sex chromosomes from either of the parents is responsible for the condition, which leads to an autosomal disorder. Apert’s syndrome: This abnormality is characterized by a dysmorphic face and severe webbing of the hands and feet.It causes a different facial appearance, affects the mental process of abstract thinking, and delays growth mostly in the age group from 14-18 and above 60 years. Down syndrome: This is a hereditary disorder caused when cell division is not normal and results in extra genetic material from chromosome 21.Syndactyly - congenital hand differences - Boston Children's Hospital Play Webbing Connected with Abnormalities Complicated webbing: Digits linked with soft and hard tissue in an abnormal shape (bones missing in between).Complex webbing: Digits connected by bone or cartilage (the soft and hard tissue).Simple webbing: Digits joined together by skin or soft tissues.Complete webbing: Webbing in which the skin is linked in the entire path up the digits with all the necessary parts.Incomplete webbing: Inappropriate webbing that takes place partially between the digits.Webbing can be associated with hereditary defects of both Down and Apert syndromes, which lead to unusual development of the bones in the hands and feet. This is unsuccessful in the case of webbed fingers and toes, which lead to digits that are combined. Image Credit: Samrith Na Lumpoon / Shutterstock Causes of Webbed Fingers and Toesĭuring the sixth or seventh week of pregnancy, the child’s hands and feet in the uterus begin to split and form fingers and toes. However, the chances for only one member in a family to have syndactyly are also commonly seen. Genetically acquired traits are thought to be a cause since relative members frequently share this condition. In few cases to date, the exact reasons for webbed fingers and toes are unknown. At this stage, the webbing disappears due to the dissolution of the tissue between the digits by an enzyme. However, during 6-8 weeks, cells' death occurs as a normal and controlled part of an organism's growth or development. In only 1 among around 3000 children, this condition occurs.ĭuring the first stage of prenatal development in humans, all the fingers and toes are fused. However, a similar condition is rare in human beings, and it is even rarer for the fingers or toes to be connected by bones. Such condition is normal (connected only by skin) in terrestrial mammals such as kangaroos, dogs, and cats, in many water-habitat birds, like ducks, and in amphibians like frogs. Syndactyly, an infrequent condition in human beings, is a state where fingers or toes are joined together.